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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 839426Generated: October 31, 2026

HCID 746766, compound → 3-[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]propanoic acid

https://huagongshe.com/reaction/839426

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 746766HCID 746766—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product3-[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]propanoic acidHCID 13661656—

Reaction Steps

A mixture of the corresponding acrylic acid derivative of Example 5 (1.0 g.) and palladium-on-charcoal (0.25 g. of 10%) in ethanol (50 ml.) was shaken in an atmosphere of hydrogen until uptake of hydrogen had ceased. Removal of the catalyst by filtration, evaporation of the filtrate and recrystallisation of the residue gave 0.25 g. of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04095025
Source datasetuspto-grants-1978_06
ORD IDord-aa84a3ea217642dab5fcbd2c7bd2c1f7
Source noteuspto-grants-1978_06