Nitric Acid → Sulfuric Acid

Participants

Reaction Steps

Into vessel 1 is charged 4-chlorobenzotrifluoride I and an acid mixture of nitric acid, sulfur trioxide and sulfuric acid. The sulfuric trioxide and sulfuric acid usually are combined as forming sulfuric acid or oleum. The molar ratio of nitric acid in the mixture to I suitably is at least 1:1, and, preferably, a slight excess of nitric acid over the 1:1 ratio is present, usually about 5-10%, i.e., a ratio of about 1.1:1, thereby ensuring substantially complete mononitration of I into II.

Provenance & Evidence