Nitric Acid → Sulfuric Acid

HRID 839528Notes

Reaction equation

HRID 839528 reaction equation
ClC1C=CC(C(F)(F)F)=CC=1.[N+]([O-])(O)=O.[S:16](=[O:19])(=[O:18])=[O:17].[S:20](=[O:24])(=[O:23])([OH:22])[OH:21]>>[S:20](=[O:22])(=[O:21])([OH:24])[OH:23].[OH:23][S:20]([OH:24])(=[O:22])=[O:21].[O:17]=[S:16](=[O:19])=[O:18]

Participants

6

Reactant 4

HCID 944Nitric AcidHCID 1118Sulfuric Acid2×HCID 73941-Chloro-4-(trifluoromethyl)benzeneHCID 24682Sulfur trioxide

Product 2

HCID 1118Sulfuric AcidHCID 24681Fuming sulfuric acid

Procedure

Into vessel 1 is charged 4-chlorobenzotrifluoride I and an acid mixture of nitric acid, sulfur trioxide and sulfuric acid. The sulfuric trioxide and sulfuric acid usually are combined as forming sulfuric acid or oleum. The molar ratio of nitric acid in the mixture to I suitably is at least 1:1, and, preferably, a slight excess of nitric acid over the 1:1 ratio is present, usually about 5-10%, i.e., a ratio of about 1.1:1, thereby ensuring substantially complete mononitration of I into II.

Sources & evidence

ORD record
ord-6cb9b142cecc47c191b42a9a635f70e4
Source dataset
uspto-grants-1978_06
Patent number
US04096195

Reaction notes

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