1,1-Ethanedithiol → 2,3-Dimercaptopropane

HRID 839744Notes

Reaction equation

HRID 839744 reaction equation
C1(C(=O)CCC(O)=O)C=CC=CC=1.[C:14]1([C:20]2([CH2:25][CH2:26]C(O)=O)[S:24]CC[S:21]2)C=CC=CC=1.[CH:30]([SH:33])([SH:32])[CH3:31]>>[CH2:20]([SH:24])[CH:25]([SH:32])[CH3:26].[CH3:14][CH:20]([SH:21])[CH:30]([SH:33])[CH3:31]

Participants

5

Reactant 3

HCID 336451,1-EthanedithiolHCID 728713-Benzoylpropionic acidHCID 543097922-Phenyl-1,3-dithiolane-2-propionic acid

Product 2

HCID 612172,3-DimercaptopropaneHCID 5483532,3-Butanedithiol

Procedure

In the same manner, 4-phenyl-4-oxobutyric acid is converted to 2-phenyl-1,3-dithiolane-2-propionic acid using ethanedithiol; while the use of 1,2-propanedithiol and 2,3-butanedithiol affords 4-methyl- and 4,5-dimethyl-2-phenyl-1,3-dithiolane-2-propionic acid, respectively.

Sources & evidence

ORD record
ord-eace0950a01d46e9bf84b497e39508fb
Source dataset
uspto-grants-1978_06
Patent number
US04096155

Reaction notes

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