Triethylamine → HCID 20322098, compound

HRID 839820Notes

Reaction equation

HRID 839820 reaction equation
[CH2:1]([O:5][CH:6]([O:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:7][NH2:8])[CH2:2][CH2:3][CH3:4].BrC[CH2:16][CH:17]1[O:22][CH:21]([CH3:23])[CH:20]([CH3:24])[CH2:19][O:18]1.C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH2:10]([O:9][CH:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])[CH2:7][NH:8][CH2:16][CH:17]1[O:22][CH:21]([CH3:23])[CH:20]([CH3:24])[CH2:19][O:18]1)[CH2:11][CH2:12][CH3:13]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 19069548HCID 19069548, compoundHCID 20322085HCID 20322085, compound

Product 1

HCID 20322098HCID 20322098, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2,2-Dibutoxyethylamine (0.11 mole), 2-bromoethyl-4,5-dimethyl-1,3-dioxane (0.1 mole), triethylamine (20 ml) and toluene (150 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction is heated at reflux for a period of about 12 hours. After this time the reaction mixture is allowed to cool to room temperature and is filtered. The reaction mixture is then stripped of solvent and unreacted starting materials under reduced pressure to yield the desired product N-(2,2-dibutoxyethyl)-N-(4,5-dimethyl-1,3-dioxan-2-ylmethyl)-amine.

Workup

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction is heated
  4. temperatureat reflux for a period of about 12 hours
  5. filtrationis filtered

Sources & evidence

ORD record
ord-4afacf46be474bd1bfd95369387b4a60
Source dataset
uspto-grants-1978_06
Patent number
US04097491

Reaction notes

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