Calcium Carbonate → HCID 86735807, compound

HRID 839895Notes

Reaction equation

HRID 839895 reaction equation
[CH3:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([C:9]1[N:13]2[CH2:14][CH2:15][CH:16]([C:17]([O-:19])=[O:18])[C:12]2=[CH:11][CH:10]=1)=[O:8].[K+].C(=O)([O-])[O-].[Ca+2:25].[Cl-].[NH4+].[Ca]>Cl.O>[CH3:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([C:9]1[N:13]2[CH2:14][CH2:15][CH:16]([C:17]([O-:19])=[O:18])[C:12]2=[CH:11][CH:10]=1)=[O:8].[Ca+2:25].[CH3:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]([C:9]1[N:13]2[CH2:14][CH2:15][CH:16]([C:17]([O-:19])=[O:18])[C:12]2=[CH:11][CH:10]=1)=[O:8]

Participants

7

Reactant 4

HCID 10112Calcium Carbonate2×HCID 25517Ammonium ChlorideHCID 5460341CalciumHCID 86735808HCID 86735808, compound2×

Product 1

HCID 86735807HCID 86735807, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

To a solution of 175 mg. of 5-(N-methyl-2-pyrroyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid in 5 ml. of methanol is added 1 molar equivalent of potassium hydroxide, in the form of a 0.1N solution, thus yielding a solution containing potassium 5-(N-methyl-2-pyrroyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate. A solution of 40 mg. of calcium carbonate dissolved in the minimum amount of 1N hydrochloric acid necessary to effect solution of the calcium carbonate, is buffered with 100 mg. of solid ammonium chloride, followed by the further addition of 5 ml. of water. The thus obtained buffered calcium solution is then added to the solution of potassium 5-(N-methyl-2-pyrroyl)-1,2-dihydro-3H-pyrrolo-[1,2-a]pyrrole-1-carboxylate and the precipitate which forms is collected by filtration, washed with water and air dried, to yield calcium 5-(N-methyl-2-pyrroyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylate.

Workup

  1. customThe thus obtained
  2. filtrationthe precipitate which forms is collected by filtration
  3. washwashed with water and air
  4. customdried

Sources & evidence

ORD record
ord-ca833fd1d3784483897f657a92a33f0c
Source dataset
uspto-grants-1978_06
Patent number
US04097579

Reaction notes

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