Ethyl trifluoroacetate → HCID 20322686, compound

HRID 839904Notes

Reaction equation

HRID 839904 reaction equation
C(O[CH:4]=[N:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[CH:8][CH:7]=1)C.[F:13][C:14]([F:21])([F:20])[C:15](OCC)=O.O.[NH2:23][NH2:24]>C(O)C.O>[Cl:12][C:9]1[CH:8]=[CH:7][C:6]([N:5]2[CH:4]=[N:24][N:23]=[C:15]2[C:14]([F:21])([F:20])[F:13])=[CH:11][CH:10]=1

Participants

5

Reactant 3

HCID 9794Ethyl trifluoroacetateHCID 24654Hydrazine hydrate (1:1)HCID 13664048HCID 13664048, compound

Product 1

HCID 20322686HCID 20322686, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

Prepared from ethyl-N-(4 -chlorophenyl)formimidate, ethyl trifluoroacetate and hydrazine hydrate using the method of Example 1, in 50% yield m.p. 108° (from ethanol/water). (Found: C, 44.03%; H, 2.11%; Cl, 14.00%; F, 23.2%; N, 16.82%. C9H5ClF3N3 requires C, 43.66%; H, 2.04%; Cl, 14.32%; F, 23.0%; N, 16.97%) δ(CDCl3): 8.37 (1H, s); 7.50 (4H, m). m/e, 247 and 249.

Sources & evidence

ORD record
ord-7a498921ec47421280d1bc8e4a0055cb
Source dataset
uspto-grants-1978_06
Patent number
US04097599

Reaction notes

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