참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetanilide | HCID 904 | — |
| 반응물 | Chloroacetyl chloride | HCID 6577 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | 4'-Chloroacetyl(acetanilide) | HCID 8805 | — |
반응 단계
23.5 mmol of chloroacetyl chloride and, in portions, 18.1 mmol of acetanilide, are added slowly, under an argon atmosphere, to 108 mmol of aluminium chloride in 90 ml of 1,2-dichloroethane. The reaction mixture is heated at 60° C. for 2 hours and then cooled with an ice bath. After slow hydrolysis using ice, and filtration, the precipitate obtained is washed with ethyl ether and dried. The expected product so obtained is used in the following without being purified.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06365605B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_04 |
|---|
| ORD ID | ord-8302ee1b619a44479dd5e646e1a4a518 |
|---|
| 출처 메모 | uspto-grants-2002_04 |
|---|
