反应详情

温度

60 °C

23.5 mmol of chloroacetyl chloride and, in portions, 18.1 mmol of acetanilide, are added slowly, under an argon atmosphere, to 108 mmol of aluminium chloride in 90 ml of 1,2-dichloroethane. The reaction mixture is heated at 60° C. for 2 hours and then cooled with an ice bath. After slow hydrolysis using ice, and filtration, the precipitate obtained is washed with ethyl ether and dried. The expected product so obtained is used in the following without being purified.

1. temperaturecooled with an ice bath
2. customAfter slow hydrolysis
3. filtrationice, and filtration
4. customthe precipitate obtained
5. washis washed with ethyl ether
6. customdried