Hydrochloric Acid → HCID 15406934, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl α,α-dimethyl-3-pyridylacetate (disclosed in EP application 0 288 279, published Oct. 26, 1988) (2.67 grams, 13.8 mmoles) was dissolved in EtOH (11.1 ml.) and a 1.0M LiOH in water (33.3 ml.) (33.4 mmoles) was added. The mixture was stirred at 25° C. for 4 hours. 1 N HCl (38.73 ml.) was added and after 5 minutes the mixture was evaporated to dryness to give the title compound (Yield: 100%).

Provenance & Evidence