HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-5,6,7,8-tetrahydronaphthalen-2-ol → 2-(5,6,7,8-Tetrahydro-3-nitro-2-naphthoxy)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 606329 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 2-(5,6,7,8-Tetrahydro-3-nitro-2-naphthoxy)-propionic acid ethyl ester | HCID 17910682 | 43% |
Reaction Steps
5,6,7,8-Tetrahydro-3-nitro-2-naphthol is alkylated according to the general instructions that are mentioned in Example A) with D,L-2-bromopropionic acid ethyl ester. After column chromatography with hexane/ethyl acetate, the nitro compound is obtained in a yield of 43%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06365736B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-4fb2c50462a64321b92c5075c8b84e67 |
| Source note | uspto-grants-2002_04 |