反应详情

20 ml of dimethylamine (40% in water) were introduced into a round-bottomed flask and a solution of 2.5 g (11.6 mmol) of 4-(allyloxycarbonyl)benzoyl chloride in 50 ml of THF was added dropwise. The reaction mixture was stirred at room temperature for 1 hour. The reaction mixture was poured into water and extracted with ethyl ether. The organic phase was separated by settling, dried over magnesium sulfate and evaporated. 2.7 g (100%) of the expected amide were recovered in the form of a slightly yellow oil.

1. extractionextracted with ethyl ether
2. customThe organic phase was separated
3. dry with materialdried over magnesium sulfate
4. customevaporated
5. custom2.7 g (100%) of the expected amide were recovered in the form of a slightly yellow oil