HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodophenylacetate → 4-[3-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)-1-propynyl]phenyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodophenylacetate | HCID 141793 | — |
| Reactant | alpha-Ethynyl-5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenemethanol | HCID 22361502 | — |
| Product | 4-[3-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)-1-propynyl]phenyl acetate | HCID 22619470 | 25% |
Reaction Steps
Following the basic procedure of Example 11(d), by reacting 1.28 g (5 mmol) of α-ethynyl-5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenemethanol with 1.44 g (5.5 mmol) of 4-iodophenyl acetate, 480 mg (25%) of the expected compound, with a melting point of 129°-130° C., were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06368608B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-24102aba141d4d6b9481cd471018b53d |
| Source note | uspto-grants-2002_04 |