HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-(methylsulphinyl)benzene → 4-(3-Hydroxy-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propynyl)phenylsulfinylmethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-(methylsulphinyl)benzene | HCID 3013958 | — |
| Reactant | alpha-Ethynyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenemethanol | HCID 11817362 | — |
| Product | 4-(3-Hydroxy-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propynyl)phenylsulfinylmethane | HCID 22619415 | — |
Reaction Steps
Following the basic procedure of Example 32, by reacting 1.21 g (5 mmol) of αethynyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenemethanol with 1.1 g (5 mmol) of 4-bromophenylsulfinylmethane, 177 mg (9%) of the expected sulfoxide compound, with a melting point of 121°-122° C., were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06368608B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-9257940612104583b854d0a90989b4b0 |
| Source note | uspto-grants-2002_04 |