HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-bromothiophene-2-carboxylate → HCID 22619465, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-bromothiophene-2-carboxylate | HCID 605713 | — |
| Reactant | alpha-Ethynyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenemethanol | HCID 11817362 | — |
| Product | HCID 22619465 | HCID 22619465 | — |
Reaction Steps
Following the basic procedure of Example 32 by reacting 1.21 g (5 mmol) of α-ethynyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenemethanol with 1.1 g (5 mmol) of methyl 5-bromo-2-thiophenecarboxylate, 371 mg (19%) of the expected methyl ester, with a melting point of 84°-85° C., were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06368608B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-40a0addc74cc4850b70fceece906986d |
| Source note | uspto-grants-2002_04 |