Potassium Carbonate → HCID 22619862, compound

Participants

Reaction Steps

A solution of 6-(2-methylpyridin-3-yloxy)-pyridazine-3-carboxylic acid hydrazide (D12) (0.62 g, 2.53 mmol) in conc. hydrochloric acid (9 ml) and water (7.5 ml) cooled to 0° C. in an ice-bath was treated with a solution of sodium nitrite (0.18 g, 2.53 mmol) in water (1.5 ml) dropwise keeping the temperature below 5° C. After 10 minutes saturated potassium carbonate was added until basic. The precipitate was filtered off, washed with water and air dried to give a cream solid (0.33 g, 51%).

Provenance & Evidence