2-(Aminomethyl)aniline → HCID 66158495, compound

HRID 840586Notes

Reaction equation

HRID 840586 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH2:5].[CH3:10][C:11]1[O:15][N:14]=[C:13]([C:16](Cl)=[O:17])[CH:12]=1>>[CH3:10][C:11]1[O:15][N:14]=[C:13]([C:16]([NH:5][CH2:4][C:3]2[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=2[NH2:1])=[O:17])[CH:12]=1

Participants

3

Reactant 2

HCID 1780962-(Aminomethyl)anilineHCID 27368945-Methylisoxazole-3-carbonyl chloride

Product 1

HCID 66158495HCID 66158495, compound

Procedure

2-Aminobenzylamine (490 mg, 4.01 mmol) and 5-methyl-3-isoxazoyl chloride (437 mg, 3.01 mmol) were converted to the title compound by the procedure of Preparation 1 to yield 250 mg. (36%). MS(FD) m/z 231 (M+). 1H NMR consistent with desired product.

Sources & evidence

ORD record
ord-c571d24560a4434e8bec82484dab27c4
Source dataset
uspto-grants-2002_04
Patent number
US06369070B1

Reaction notes

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