HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-methyl 2-hydroxy-3-phenylpropanoate → (2S)-2-[4-(2-benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';3',1'']terphenyl-4'-yloxy]-3-phenyl-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-methyl 2-hydroxy-3-phenylpropanoate | HCID 5289077 | — |
| Reactant | 4-(2-Benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';3',1'']terphenyl-4'-ol | HCID 10672435 | — |
| Product | (2S)-2-[4-(2-benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';3',1'']terphenyl-4'-yloxy]-3-phenyl-propionic acid | HCID 9830685 | — |
Reaction Steps
The title compound was prepared from 4-(2-benzyl-benzofuran-3-yl)-4″-methoxy-[1,1′;3′,1″]terphenyl-4′-ol, and (S)-(−)-3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h , and was obtained as a white solid, mp 73-75° C.; MS m/e 629 (M−H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06369072B2 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-f37e8fc864304ccfbc40fc52c65b1ffc |
| Source note | uspto-grants-2002_04 |