HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → HCID 77750383, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 1-Hydroxybenzotriazole hydrate | HCID 2796029 | — |
| Reactant | HCID 77750217 | HCID 77750217 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 77750383 | HCID 77750383 | — |
Reaction Steps
N,N-Diisopropylethylamine (3 eq) was added to a solution of 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (1.5 eq), 1-hydroxybenzotriazole hydrate (1.5 eq), benzylamine (2 eq) and the product of Example 1, step c) (1 eq) in DMF (20 ml). The reaction mixture was stirred at room temperature for 2 hours then added dropwise to stirred acidic ice-water. The subtitle compound was isolated by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06369064B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-780ce48b6a984cfb8d0109af2ee8d70b |
| Source note | uspto-grants-2002_04 |