Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 840728Generated: October 31, 2026

3,4-Dichlorophenyl isocyanate → 5-Methoxy-3-(4-(3,4-dichlorophenylaminocarbonylamino)-3-methylphenyl)-3H-(1,3,4)-oxadiazol-2-one

https://huagongshe.com/reaction/840728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dichlorophenyl isocyanateHCID 7607—
Reactant5-methoxy-3-(4-amino-3-methylphenyl)-3H-(1,3,4)-oxadiazol-2-oneHCID 9877857—
SolventTolueneHCID 1140—
Product5-Methoxy-3-(4-(3,4-dichlorophenylaminocarbonylamino)-3-methylphenyl)-3H-(1,3,4)-oxadiazol-2-oneHCID 69970341—

Reaction Steps

The latter compound was obtained by reacting 5-methoxy-3-(4-amino-3-methylphenyl)-3H-(1,3,4)oxadiazol-2-one with equimolar amounts of 3,4-dichlorophenyl isocyanate in toluene at 50° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06369088B2
Source datasetuspto-grants-2002_04
ORD IDord-0635da5948b94429b205f91722f74981
Source noteuspto-grants-2002_04