4-[(methylsulfonyl)methyl]aniline(SALTDATA: FREE) → HCID 178504867, compound

HRID 840876Notes

Reaction equation

HRID 840876 reaction equation
C(O[CH:4]=[C:5]1[C:16]2[C:8](=[CH:9][CH:10]=[C:11]3[C:15]=2[S:14][CH:13]=[N:12]3)[NH:7][C:6]1=[O:17])C.[CH3:18][S:19]([CH2:22][C:23]1[CH:29]=[CH:28][C:26]([NH2:27])=[CH:25][CH:24]=1)(=[O:21])=[O:20]>>[CH3:18][S:19]([CH2:22][C:23]1[CH:29]=[CH:28][C:26]([NH:27][CH:4]=[C:5]2[C:16]3[C:8](=[CH:9][CH:10]=[C:11]4[C:15]=3[S:14][CH:13]=[N:12]4)[NH:7][C:6]2=[O:17])=[CH:25][CH:24]=1)(=[O:20])=[O:21]

Participants

3

Reactant 2

HCID 128439644-[(methylsulfonyl)methyl]aniline(SALTDATA: FREE)HCID 539908078-[Ethoxymethylidene]-6H-[1,3]thiazolo[5,4-e]indol-7-one

Product 1

HCID 178504867HCID 178504867, compoundYield 66%

Procedure

The title compound was prepared in 66% yield from 8-ethoxymethylene-6,8-dihydro-1-thia-3,6-diaza-as-indacen-7-one and 4-methylsulfonylmethylaniline according to Procedure J: 1H NMR (DMSO-d6): δ11.1 (d, 1H), 11.0 (s, 1H), 9.3 (s, 1H), 8.1 (d, 1H), 7.8 (d, 1H), 7.5 (q, 4H), 7.1 (d, 1H), 4.45 (s, 2H), 2.9 (s. 3H); APCI−MS m/z 384 (M−H)−.

Sources & evidence

ORD record
ord-3ed5f4027bff46e0b6cfcceb6367ea9b
Source dataset
uspto-grants-2002_04
Patent number
US06369086B1

Reaction notes

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