Chloride → HCID 178466659, compound

Participants

Reaction Steps

The compound (V) was prepared according to the procedure described in Example 1 for the synthesis of (XIX), starting from 5,6 g of the chloride of acetylsalicylic acid, 3.8 ml of TEA and 1.06 g of 1.2-propanediol. The product was purified by flash chromatography utilizing an eluent mix constituted by ethylether/hexane 6:4 (v/v). The intermediate fractions were collected, the solvent was evaporated under reduced pressure and 0.55 g of 1.2-propanediol-bis-acetylsalicylate (V) were obtained.

Provenance & Evidence