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HRID84147

反应详情

EQUATION

反应方程式

HRID 84147 的结构方程式

REACTANTS

反应物

4
结构：ClC(Cl)Cl
HCID6212

Chloroform

CHCl3

结构：CCCCCCCCN
HCID8143

1-Octanamine

C8H19N

结构：CCN1c2ccccc2C(CS(=O)(=O)N2CCC(C(=O)OC)CC2)=CC1(C)C
HCID12138183

未命名化合物

结构：COc1ccc2c(c1)N(C)C(C)(C)CC2CS(=O)(=O)Cl
HCID12138193

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCNS(=O)(=O)CC1CC(C)(C)N(C)c2cc(OC)ccc21
HCID12138195

未命名化合物

收率 69%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CCO
溶剂HCID702

Ethanol

C2H6O

结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

(1-Methyl-7-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroquinol-4-yl)-N-octyl-methane-sulfonamide (21) is prepared similarly to compound (10) from compound (19) and n-octylamine in dry acetonitrile. It is isolated by column chromatography on silica gel using a gradient running from chloroform to ethanol.

WORKUP

后处理

  1. customIt is isolated by column chromatography on silica gel using a gradient