HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 76035018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | PyBOP | HCID 2724699 | — |
| Reactant | O-(Tetrahydropyran-2-yl)hydroxylamine | HCID 5142091 | — |
| Catalyst | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 76035018 | HCID 76035018 | — |
Reaction Steps
Compound 19 was synthesized via the route as shown in Scheme 4 above (reagents and conditions: a) NH2OTHP, PyBOP, NEt3, DMF; b) Benzenesulfonyl chloride, KOH, tetra-n-butylammonium bisulfate, CH2Cl2; c) TFA, MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846748B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-82d0905237514c43835b88e5d1b74944 |
| Source note | uspto-grants-2014_09 |