HRID84193

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID6422

未命名化合物

HCID7369

Benzenesulfonyl chloride

C6H5ClO2S

HCID14797

Potassium hydroxide

HKO

结构：F[P-](F)(F)(F)(F)F.c1ccc2c(c1)nnn2O[P+](N1CCCC1)(N1CCCC1)N1CCCC1

HCID2724699

PyBOP

C18H28F6N6OP2

HCID5142091

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

C5H11NO2

PRODUCTS

生成物

结构：O=C(C=Cc1cn(S(=O)(=O)c2ccccc2)c2ccccc12)NO

HCID76035018

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

结构：CCCC[N+](CCCC)(CCCC)CCCC.O=S(=O)([O-])O

催化剂HCID94433

未命名化合物

溶剂HCID887

Methanol

CH4O

溶剂HCID6344

Dichloromethane

CH2Cl2

溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

Compound 19 was synthesized via the route as shown in Scheme 4 above (reagents and conditions: a) NH2OTHP, PyBOP, NEt3, DMF; b) Benzenesulfonyl chloride, KOH, tetra-n-butylammonium bisulfate, CH2Cl2; c) TFA, MeOH).