Diethyl methylmalonate → HCID 70146028, compound

HRID 842277Notes

Reaction equation

[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16]I)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:18]([O:20][C:21](=[O:29])[CH:22]([CH3:28])[C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH3:19]>>[CH2:18]([O:20][C:21](=[O:29])[C:22]([CH2:16][CH2:15][C:11]1[CH:12]=[CH:13][CH:14]=[C:9]([O:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH:10]=1)([CH3:28])[C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH3:19]

Participants

Reactant 2

HCID 11857Diethyl methylmalonate

HCID 22618913HCID 22618913, compound

Product 1

HCID 70146028HCID 70146028, compound

Procedure

2-(3-Benzyloxyphenyl)ethyl iodide and 2-methylmalonic acid diethyl ester were used in the same manner as working example 52 (3) to give the subject compound.

Workup

customto give the subject compound

Sources & evidence

ORD record: ord-5cd5aba319a74ee1aa1b168740493727
Source dataset: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06372800B1

Reaction notes

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