HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Aminocaproic Acid, Benzyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 14420167 | HCID 14420167 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Aminocaproic Acid, Benzyl Ester | HCID 14083108 | 151.1% |
Reaction Steps
To N-Boc-aminocaproic acid, benzyl ester (1.125 g, 3.50 mmol) in dichloromethane (4 ml) was added trifluoroacetic acid (8 ml) and the mixture stirred at room temperature for 10 minutes. The solvents were removed in vacuo to give the title compound (1.17 g, 100%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06375926B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-074dde48283b48059e07493826c36d43 |
| Source note | uspto-grants-2002_04 |