Sodium ethoxide → HCID 12017029, compound

HRID 842440Notes

Reaction equation

HRID 842440 reaction equation
[CH3:1][C@@H:2]1[CH2:8][CH2:7][C@@H:6]2[CH2:9][C@H:3]1[C:4](=[O:10])[O:5]2.[CH3:11][CH2:12][O-:13].[Na+]>C(O)C>[OH:13][C@H:12]1[CH2:9][C@@H:3]([C:4]([O:5][CH2:6][CH3:7])=[O:10])[C@H:2]([CH3:8])[CH2:1][CH2:11]1

Participants

4

Reactant 2

HCID 2723922Sodium ethoxideHCID 11286510HCID 11286510, compound

Product 1

HCID 12017029HCID 12017029, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

reacting said (1R,2R,5R)-2-methyl-6-oxabicyclo[3.2.1]octan-7-one (9) with with EtONa and ethanol, or with Na and ethanol to produce ethyl (1R,2R,5R)-5-hydroxy-2-methylcyclohexane-1-carboxylate (10),

Sources & evidence

ORD record
ord-3848704eb6f94defb4070d9fe485d36f
Source dataset
uspto-grants-2002_04
Patent number
US06375943B1

Reaction notes

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