反应详情

910 mg (3.0 mmol) of 8-bromo-9-benzyladenine and 1.08 g of sodium hydrosulfide were added to 50 ml of ethanol and heated for 12 hr under refluxing. After the solvent was removed by distillation, the reaction product was dissolved in distilled water and neutralized with 1 N hydrochloric acid. Deposited crystals were collected by filtration to thereby obtain the captioned compound (770 mg; yield: 99%).

1. temperatureheated for 12 hr
2. temperatureunder refluxing
3. customAfter the solvent was removed by distillation
4. dissolutionthe reaction product was dissolved in distilled water and neutralized with 1 N hydrochloric acid
5. filtrationDeposited crystals were collected by filtration
6. customto thereby obtain the captioned compound (770 mg; yield: 99%)