HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 5-bromothiophene-2-carboxylate → 5-(3-Benzyloxycarbonylamino-prop-1-ynyl)-thiophene-2-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 5-bromothiophene-2-carboxylate | HCID 10912335 | — |
| Reactant | Benzyl prop-2-yn-1-ylcarbamate | HCID 11137906 | — |
| Product | 5-(3-Benzyloxycarbonylamino-prop-1-ynyl)-thiophene-2-carboxylic acid tert-butyl ester | HCID 54528964 | — |
Reaction Steps
The title compound of Step B was prepared from prop-2-ynyl-carbamic acid benzyl ester and 5-bromo-thiophene-2-carboxylic acid tert-butyl ester in an analagous manner to Step A of Preparation 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376502B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-cf685f3ea09c482aa35952ad6d707ee5 |
| Source note | uspto-grants-2002_04 |