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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 842740Generated: October 30, 2026

Methyl 5-bromofuran-2-carboxylate → Methyl 5-(3-((tert-butoxycarbonyl)amino)prop-1-yn-1-yl)furan-2-carboxylate

https://huagongshe.com/reaction/842740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 5-bromofuran-2-carboxylateHCID 599633—
Reactanttert-butyl N-(prop-2-yn-1-yl)carbamateHCID 11073648—
ProductMethyl 5-(3-((tert-butoxycarbonyl)amino)prop-1-yn-1-yl)furan-2-carboxylateHCID 53793873—

Reaction Steps

The title compound of Step A was prepared from 5-bromo-furan-2-carboxylic acid methyl ester and prop-2-ynyl-carbamic acid tert-butyl ester as described in Step A of Preparation 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06376502B1
Source datasetuspto-grants-2002_04
ORD IDord-0ef005a91f5d4352b8a7cf124402989d
Source noteuspto-grants-2002_04