Benzyl Chloride → 1-Bromo-4-phenylmethoxybenzene

Participants

Reaction Steps

The intermediate 32 (1.76 g), 4-benzyloxyphenyl boric acid [6.75 g, 4-benzyloxy bromobenzene was prepared according to a process described in the process c-1 in example 1 from 4-bromophenol (Tokyo Chemical Ind. Co., Ltd.) and benzyl chloride (Tokyo Chemical Ind. Co., Ltd.), and the product was prepared according to a method described in the reference Y Satoh et al. SYNTHESIS page 1146, 1994], anhydrous potassium carbonate (4.09 g) and tetrakis (triphenylphosphine)palladium (0)(342 mg) were reacted according to the method described in the process i in example 23 to obtain the compound in the title (2.30 g).

Provenance & Evidence