HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22616533, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 22616586 | HCID 22616586 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 22616533 | HCID 22616533 | — |
Reaction Steps
The compound in the title (366 mg) was obtained by reacting the intermediate 62 (455 mg) with triethylamine (2.0 ml) in the mixture of purified water (2 ml) and tetrahydrofuran (10 ml) according to the process described in the process a in example 1. Proviso that the reaction was carried out for 10 days. Rf 0.60 (chloroform:methanol=10:1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376546B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-b30643359b994ef1aa144d753e01b06a |
| Source note | uspto-grants-2002_04 |