Ammonia → HCID 178512062, compound

Participants

Reaction Steps

To a mixture of 40 ml of ethanol and 10 ml of 28% aqueous ammonia was added 3.9 g (10.0 mmol) of N-(2,6-dichloro-4-trifluoromethylphenyl)-2,2,3,3,3-pentafluoropropionimidoyl chloride, and the mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated, and water was poured into the residue, which was then extracted with ethyl acetate. The organic layer was dried over anhydrous magnesium sulfate and then concentrated under reduced pressure to give 3.70 g of N-(2,6-dichloro-4-trifluoromethylphenyl)-2,2,3,3,3-pentafluoropropionamidine (hereinafter referred to as present compound 4).

Provenance & Evidence