HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 131723200, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 131723199 | HCID 131723199 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131723200 | HCID 131723200 | 110.4% |
Reaction Steps
Methyl 2-{N-methyl-N-[(R/S)-α-t-butoxycarbonylmethyl-4-(3,5-bistrifluoromethylbenzyloxy)phenylacetyl]amino}-(R)-propionate 48e (1.46 g, 2.47 mmol) was treated with 50% TFA in CH2Cl2 (20 mL) for 1 hour and the solution was concentrated in vacuo to give the acid (1.46 g, 100%) as a syrup. MS (ESI): (M+H)+=535.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376665B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-425ac29c3e2a4bdfa67f98c794c86548 |
| Source note | uspto-grants-2002_04 |