Isonicotinic Acid → HCID 70156977, compound

HRID 843955Notes

Reaction equation

HRID 843955 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][CH:7]([N:15]([CH3:17])[CH3:16])[CH2:6][C:5]2=1.[N:18]1[CH:23]=[CH:22][C:21]([C:24](O)=[O:25])=[CH:20][CH:19]=1>>[N:18]1[CH:23]=[CH:22][C:21]([C:24]([NH:1][C:2]2[CH:3]=[C:4]3[C:12](=[CH:13][CH:14]=2)[NH:11][C:10]2[CH2:9][CH2:8][CH:7]([N:15]([CH3:17])[CH3:16])[CH2:6][C:5]3=2)=[O:25])=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 5922Isonicotinic AcidHCID 226115606-amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole

Product 1

HCID 70156977HCID 70156977, compoundYield 37.4%

Procedure

Beginning with 9.2 mg (0.040 mMol) 6-amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole and 12.5 mg (0.101 mMol) 4-pyridinecarboxylic acid, 5.0 mg (37%) of the title compound were recovered as a beige solid.

Sources & evidence

ORD record
ord-aea72e5e197d4782a0be0c76d01d3dcc
Source dataset
uspto-grants-2002_04
Patent number
US06380201B1

Reaction notes

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