反应详情

To a solution of 2-Oxo-2,3-dihydro-1H-indole-5-carbonitrile (1.3 g) in methanol (30 ml) was added 10% PtO2 (0.200 g). This was shaken under 44 psi hydrogen over night. The catalyst was removed by filtration, and the mixture was dried over Na2SO4. The solution was concentrated to give a yellow solid, (1.1 g). MW 162; MS (m/e) 162 (M+).

1. customThe catalyst was removed by filtration
2. dry with materialthe mixture was dried over Na2SO4
3. concentrationThe solution was concentrated
4. customto give a yellow solid, (1.1 g)