HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-(3-Chloro-phenoxy)-N-(2-hydroxy-1-phenyl-ethyl)-nicotinamide → (R)-2-(3-Chloro-phenoxy)-3-(4-phenyl4,5-dihydro-oxazol-2-yl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-(3-Chloro-phenoxy)-N-(2-hydroxy-1-phenyl-ethyl)-nicotinamide | HCID 53928194 | — |
| Reactant | HCID 178513660 | HCID 178513660 | — |
| Product | (R)-2-(3-Chloro-phenoxy)-3-(4-phenyl4,5-dihydro-oxazol-2-yl)-pyridine | HCID 54499932 | — |
Reaction Steps
The compound of Example 129 was prepared according to the procedure of Example 128 substituting the corresponding hydroxy nicotinamide for (R)-2-(3-Chloro-phenoxy)-N-(2-hydroxy-1-phenyl-ethyl)-nicotinamide. The duration of reaction was between 1 and 24 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380218B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-675c3815f7b0471a919d5dffb85c52ab |
| Source note | uspto-grants-2002_04 |