Lithium Hydroxide → HCID 510684, compound

Participants

Reaction Steps

In a similar manner to example AI-2-1, 4-(3-dibenzylaminophenyl)-2,4-dioxobutanoic acid ethyl ester (0.489 g, 1.1 mmol) was reacted with 3 ml 1N LiOH in 10 ml THF to yield 0.4 g (94%) of AV-3-1 as an orange resin. 1H NMR (400 MHz, CDCl3) δ4.71 (s, 4H), 6.96 (dt, 1H, J=7.33, 2.20 Hz).

Provenance & Evidence