反应详情

A four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer was charged with 93.0 g (0.5 mol) of p-toluenesulfonohydrazide and 700 ml of methanol, and 63.6 g (0.6 mol) of benzaldehyde was dropwise added thereto in one hour while stirring at room temperature and heated under reflux for about 5 hours. The reaction liquid was cooled down to 20° C. or lower, and then crystal was filtered off and dried under reduced pressure, whereby white crystal was obtained.

1. customA four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer
2. additionwas dropwise added
3. temperatureheated
4. temperatureunder reflux for about 5 hours
5. customThe reaction liquid
6. temperaturewas cooled down to 20° C.
7. filtrationlower, and then crystal was filtered off
8. customdried under reduced pressure, whereby white crystal
9. customwas obtained