Cesium carbonate → HCID 15427532, compound

Participants

Reaction Steps

A solution of 500 mg of “B” and 238 mg of 3-hydroxybenzonitrile in 10 ml of acetonitrile is treated with 652 mg of caesium carbonate and stirred at room temperature for 40 hours. After customary working up, the residue is chromatographed on a reversed-phase column using acetonitrile/water 65:35. 3′-(3-Cyanophenoxymethyl)biphenyl-3-carbonitrile (“C”), FAB 311, is obtained as a colourless solid.

Provenance & Evidence