N,N-Dimethylethylenediamine → HCID 44241763, compound

HRID 84500Notes

Reaction equation

HRID 84500 reaction equation
Br[CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[C:12]3[S:13][C:14]([C:16]([N:18]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=4[Cl:26])[CH3:19])=[O:17])=[CH:15][C:11]=3[CH2:10][CH2:9][O:8][C:7]=2[CH:27]=1.[CH3:28][N:29]([CH3:33])[CH2:30][CH2:31][NH2:32]>>[Cl:26][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[N:18]([CH3:19])[C:16]([C:14]1[S:13][C:12]2[C:6]3[CH:5]=[CH:4][C:3]([CH2:2][NH:32][CH2:31][CH2:30][N:29]([CH3:33])[CH3:28])=[CH:27][C:7]=3[O:8][CH2:9][CH2:10][C:11]=2[CH:15]=1)=[O:17]

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 568341528-(Bromomethyl)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

Product 1

HCID 44241763HCID 44241763, compound

Procedure

8-(Bromomethyl)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide was reacted with N1,N1-dimethylethane-1,2-diamine using the procedure of Example 153 to give 197.

Sources & evidence

ORD record
ord-3e2f02d641f34ffdbd331eef46422146
Source dataset
uspto-grants-2014_09
Patent number
US08846762B2

Reaction notes

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