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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845017Generated: October 30, 2026

Ethanol → 2-(4-methoxyphenyl)pyrazine

https://huagongshe.com/reaction/845017

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantEthylenediamineHCID 3301—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 21298530HCID 21298530—
Product2-(4-methoxyphenyl)pyrazineHCID 1127545537%

Reaction Steps

The procedure of Example 1 was repeated, using 10.68 g (0.178 mol) of ethylenediamine, 27.0 g (0.148 mol) of 4-methylphenylglyoxal monohydrate, 200 ml of ethanol and 9.01 g of potassium hydroxide. 10.1 g of the titled compound was produced (yield: 37%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04755514
Source datasetuspto-grants-1988_07
ORD IDord-cccb62186aa54415b54b0bcd76789633
Source noteuspto-grants-1988_07