Hydrazine hydrate (1:1) → HCID 20133456, compound

Participants

Reaction Steps

By a method similar to that described in Preparation 3, treatment of 5-methoxy-1-indanone with glyoxylic acid hydrate and hydrazine hydrate gave 7-methoxy-[5H]-indeno-[1,2-c]pyridazin-3[2H]-one (m.p. 280°-4°, from concentrated hydrochloric acid); ν(Nujol mull) 3350-2200, 1680, 1610, 1580, 1259 and 1041 cm-1 ; δ(DMSO-d6) 2.80 (4H,s,5,6-H2), 3.73 (3H,s,CH3O), 6.74 (1H,s,4-H) 7.00 (1H, dd,8-H), 7.29 (1H,dd,9-H), 7.55 (1H,dd,10-H), 12.86 (1H,br,NH).

Provenance & Evidence