反应详情

3.28 g (20 mmol) of 5,6-dichloro-3-pyridinol in 15 ml of glacial acetic acid were N-oxidized at 100° C. using 2.14 g (21 mmol) of 35% hydrogen peroxide. When the reaction was complete, the mixture was neutralized, extracted with ethyl acetate and washed until neutral, and the solvent was removed by evaporation.

1. customwere N-oxidized at 100° C.
2. extractionextracted with ethyl acetate
3. washwashed until neutral, and the solvent
4. customwas removed by evaporation