HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-Chloro-3-phenylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-Hydroxy-3-phenylpyridine | HCID 2762808 | — |
| Product | 2-Chloro-3-phenylpyridine | HCID 2762807 | 17% |
Reaction Steps
Using the procedure given above in Example 1, 3-methyl-2(1H)-pyridone (VIII) was refluxed in phosphorus oxychloride followed by work-up to give a 17% yield of 2-chloro-3-methylpyridine (VI).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04757073 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-d1680a9b9c964968a80146063ad902ef |
| Source note | uspto-grants-1988_07 |