Piperazine → HCID 20132430, compound
Reaction equation
Cl[C:2]1[C:7]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:6][CH:5]=[CH:4][N:3]=1.[NH:14]1[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1>>[CH3:13][C:10]1[O:9][C:8]([C:7]2[C:2]([N:14]3[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)=[N:3][CH:4]=[CH:5][CH:6]=2)=[N:12][N:11]=1Participants
3
Procedure
This intermediate compound was synthesized from 2-chloro-3-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (prepared according to J. Heterocyclic Chemistry, 17, 425 (1980)) and piperazine using the procedure of Example 6.
Sources & evidence
- ORD record
- ord-e10fa90ecc1443caac05845a086d1894
- Source dataset
- uspto-grants-1988_07
- Patent number
- US04757073
Reaction notes
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