HRID845258

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O

HCID367507

Ethyl 2-[(3-nitrophenyl)methylidene]-3-oxobutanoate

C13H13NO5

HCID67903522

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3C2=O)C1c1cccc([N+](=O)[O-])c1

HCID13563415

未命名化合物

收率 89%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Prepared by a method analogous to that of Example 1(a) from 15.80 g (60 mmol) of 2-(3-nitrobenzylidene)-acetoacetic acid ethyl ester and 16.46 g (60 mmol) of 3-amino-crotonic acid-(2-phthalimidoethyl)ester in ethanol. 27.75 g (89%) of yellow crystals melting at 194°-195° C. are obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-799ad69f58d540a6b6fd8df85bb0bc72
来源数据集: uspto-grants-1988_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04757080
来源说明: uspto-grants-1988_07

反应 SMILES

[CH2:1]([O:3][C:4](=[O:19])[C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=1)[C:6]([CH3:8])=O)[CH3:2].[C:20]1(=[O:39])[N:24]([CH2:25][CH2:26][O:27][C:28](=[O:33])/[CH:29]=[C:30](\[NH2:32])/[CH3:31])[C:23](=[O:34])[C:22]2=[CH:35][CH:36]=[CH:37][CH:38]=[C:21]12>C(O)C>[CH3:8][C:6]1[NH:32][C:30]([CH3:31])=[C:29]([C:28]([O:27][CH2:26][CH2:25][N:24]2[C:23](=[O:34])[C:22]3=[CH:35][CH:36]=[CH:37][CH:38]=[C:21]3[C:20]2=[O:39])=[O:33])[CH:9]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=2)[C:5]=1[C:4]([O:3][CH2:1][CH3:2])=[O:19]