Hydrazine hydrate (1:1) → 1,4-Dihydro-2,6-dimethyl-3-ethoxycarbonyl-4-(3-nitrophenyl)-5-(2-aminoethoxy)carbonyl-pyridine

Participants

Reaction Steps

Prepared by a method analogous to that of Example 1(b) from 20.78 g (40 mmol) of 1,4-dihydro-2,6-dimethyl-3-ethoxycarbonyl-4-(3-nitrophenyl)-5-(2-phthalimidoethoxy)carbonyl-pyridine and 5.83 ml (120 mmol) of hydrazine hydrate. 13.39 g (86%) of yellow crystals, melting point 137°-139° C.

Provenance & Evidence