Hydrazine hydrate (1:1) → HCID 14076000, compound

HRID 845263Notes

Reaction equation

[CH3:1][C:2]1[NH:3][C:4]([CH3:41])=[C:5]([C:21]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][N:30]2C(=O)C3=CC=CC=C3C2=O)=[O:22])[CH:6]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)[C:7]=1[C:8]([O:10][CH3:11])=[O:9].O.NN>>[CH3:1][C:2]1[NH:3][C:4]([CH3:41])=[C:5]([C:21]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][NH2:30])=[O:22])[CH:6]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)[C:7]=1[C:8]([O:10][CH3:11])=[O:9]

Participants

Reactant 2

HCID 24654Hydrazine hydrate (1:1)

HCID 13799834HCID 13799834, compound

Product 1

HCID 14076000HCID 14076000, compound

Procedure

Prepared by a method analogous to that of Example 1(b) from 15.0 g (26 mmol) of 1,4-dihydro-2,6-dimethyl-3-methoxycarbonyl-4-(3-nitrophenyl)-5-(6-phthalimidohexyloxy)carbonyl-pyridine and 3.9 ml (80 mmol) of hydrazine hydrate. 11.2 g (97%) of an orange coloured oil.

Sources & evidence

ORD record: ord-60b5acb3ca56471798446d185c1ec9a9
Source dataset: uspto-grants-1988_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04757080

Reaction notes

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